KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKA
All Species:
27.88
Human Site:
T292
Identified Species:
40.89
UniProt:
O14965
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14965
NP_003591.2
403
45809
T292
R
R
T
T
L
C
G
T
L
D
Y
L
P
P
E
Chimpanzee
Pan troglodytes
XP_525364
403
45791
T292
R
R
T
T
L
C
G
T
L
D
Y
L
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
T364
R
R
K
T
M
C
G
T
L
D
Y
L
P
P
E
Dog
Lupus familis
XP_853397
405
45606
T293
R
R
T
T
L
C
G
T
L
D
Y
L
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P97477
395
44754
T283
R
R
T
T
M
C
G
T
L
D
Y
L
P
P
E
Rat
Rattus norvegicus
P59241
397
44856
T285
R
R
T
T
L
C
G
T
L
D
Y
Q
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
P197
G
T
L
D
Y
L
P
P
E
M
I
E
G
R
M
Chicken
Gallus gallus
XP_425725
409
46456
A295
D
F
G
W
S
V
H
A
P
S
S
R
R
S
T
Frog
Xenopus laevis
Q91819
408
46443
T299
R
R
T
T
L
C
G
T
L
D
Y
L
P
P
E
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
D214
R
T
M
C
G
T
L
D
Y
L
P
P
E
M
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
M222
L
D
Y
L
P
P
E
M
V
D
G
N
S
Y
D
Honey Bee
Apis mellifera
XP_395732
327
37711
T221
A
P
S
S
R
R
N
T
L
C
G
T
L
D
Y
Nematode Worm
Caenorhab. elegans
O01427
305
34731
N199
Y
L
P
P
E
M
V
N
G
A
D
H
S
D
A
Sea Urchin
Strong. purpuratus
XP_001181990
278
32048
P172
C
G
T
M
D
Y
L
P
P
E
M
I
E
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
G176
N
R
R
R
T
M
C
G
T
L
D
Y
L
P
P
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
V261
P
E
N
R
R
K
T
V
C
G
T
I
D
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
47.7
89.8
N.A.
82.6
83.6
N.A.
65.5
73.1
65.9
53.3
N.A.
38.4
53
46.6
50.6
Protein Similarity:
100
100
62.2
93
N.A.
86.8
87.3
N.A.
70.2
82.8
77.2
65.7
N.A.
57.8
67
56.3
60
P-Site Identity:
100
100
86.6
100
N.A.
93.3
93.3
N.A.
0
0
100
6.6
N.A.
6.6
13.3
0
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
0
0
100
6.6
N.A.
20
26.6
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
57.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% A
% Cys:
7
0
0
7
0
44
7
0
7
7
0
0
0
0
0
% C
% Asp:
7
7
0
7
7
0
0
7
0
50
13
0
7
13
7
% D
% Glu:
0
7
0
0
7
0
7
0
7
7
0
7
13
0
44
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
7
0
7
0
44
7
7
7
13
0
7
7
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
13
0
0
7
% I
% Lys:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
7
7
7
32
7
13
0
50
13
0
38
13
0
7
% L
% Met:
0
0
7
7
13
13
0
7
0
7
7
0
0
7
7
% M
% Asn:
7
0
7
0
0
0
7
7
0
0
0
7
0
0
0
% N
% Pro:
7
7
7
7
7
7
7
13
13
0
7
7
44
50
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
50
50
7
13
13
7
0
0
0
0
0
7
7
7
7
% R
% Ser:
0
0
7
7
7
0
0
0
0
7
7
0
13
7
0
% S
% Thr:
0
13
44
44
7
7
7
50
7
0
7
7
0
0
7
% T
% Val:
0
0
0
0
0
7
7
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
7
7
0
0
7
0
44
7
0
13
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _